Canadian Pharmacy: Don`t Overcook

DON’T OVERCOOK, FERMENT

By going to such an extreme, we have destroyed a lot of nutrients, vitamins and proteins (including enzymes) that are essential to optimal health. When spinach is overcooked, it loses its bright green color and turns pale forest green. The color change indicates that the wonderful chlorophyll molecules that provide blood-building nutrients have lost their effective magnesium centerpiece. Don`t Overcook

Consuming foods raw or fermented is highly recommended Viagra online. Prior to the widespread manufacturing of refrigerators in the 1940s, nearly everybody fermented or pickled vegetables and meats as a method of preserving. Cultures all over the world ferment grapes for wine and dairy for kefir, whey and cheese. Soybeans were fermented for tempeh and miso, bok choy for kimchi, cabbage for sauerkraut, wheat for beer or sourdough. In the south, Polynesians ferment taro for poi. In the north, Eskimos ferment meats, cod liver, and fish to produce “high meat”. The Swedish ferment Baltic herring to make “Surstrdm-ming”. The Koreans ferment skate, a cartilaginous fish, for “Hongeohoe” and the Japanese ferment mackerel and exocoetidae, also known as flying fish, to produce the odorous dish called “Kusaya”.

The process of fermentation allows strains of beneficial bacteria that are probiotic (pro means “for” and biotic means “life”) to thrive in our foods. Besides being an excellent method of preserving foods, fermentation replenishes the healthy bacteria (gut flora) in our digestive tracts. Vegetable-based ferments are mainly anaerobic lacto-fermented while high meats are primarily aerobically fermented, so the presence of a constant oxygen supply is integral.

Scientists have found that bacterial cells in the human body outnumber human cells ten to one. Commonly researched strains of beneficial bacteria include Lactobacillus acidophilus, Bifidobacterium longum, Lactobacillus paracasei and Saccharomyces cerevisiae boulardii. The mixed community of these bacterial cells does not threaten us but instead offers vital help with basic physiological processes, including immune self-defense. For example Saccharomyces boulardii is effective in preventing and treating patients who have develop diarrhea and colitis due to antibiotic resistant Clostridium difficile.

In addition to fighting antibiotic induced infections, these beneficial bacteria help digest foods during the fermentation process, then release those nutrients that we ourselves cannot manufacture directly from the foods. They support the further breakdown of foods, enhance the body’s ability to absorb essential dietary minerals, help produce specific nutrients (such as Vitamin K), and improve the absorption of water and lipids in the gastrointestinal tract. Fermentation enables preparation and storage of foods to retain and, in many cases, augment nutritional value. I recommend Wild Fermentation by Sandor Katz as your first guide in learning how to ferment. You will have a lifetime of recipes to explore in just that one book alone.

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Risk of relapse as the number of asthma triggers increases and Treatment ED

This study confirms previous findings that a substantial proportion of patients treated in the ED suffer a relapse within days to weeks after ED discharge. Although there is no common definition of an “acceptable” relapse rate, 17% certainly represents a high failure rate. In this study, we have confirmed that easily ascertainable historical features define patients at highest risk. Since the National Asthma Education and Prevention Program guidelines allow for physician discretion in the disposition of patients with moderate airflow limitation after treatment, these higher-risk patients may be appropriate for inpatient or observation unit care. erectile dysfunction

Patients with a number of recent ED or urgent clinic visits, multiple asthma triggers, longer duration of symptoms, or already using home nebulizers may be appropriate for admission, observation unit care, or close outpatient follow-up. There is not a consistent increase in risk of relapse as the number of asthma triggers increases, suggesting the lack of a linear dose response relationship. We cannot, however, quantify the exposure to each of these triggers so that it is difficult to make such a conclusion. Further, patients with symptoms for 7 days have a lower risk of relapse, suggesting that patients with chronic symptoms respond differently following acute therapy with Kamagra Australia. Possibly the chronic nature of their symptoms makes them less likely to return for acute care.

Recent evidence indicates that ED visits can be reduced by educational intervention. Over the longer term, some clinicians have found that intensive management programs may prevent ED visits for acute asthma. Irwin et all developed a systematic management protocol based in a pulmonary outpatient clinic. Patients underwent intensive investigation to validate the diagnosis of asthma and also were evaluated for gastroesophageal reflux disease. Patients had medication adjustments, including initiation of treatment with inhaled steroids, appropriate use of inhaled 3-agonists, and consideration of the use of other anti-inflammatory medications and Generic viagra online.

Using this comprehensive management scheme, the authors report that they were able to control “difficult” asthma 74% of the time. Similarly, Mayo et al found that a focused management program with easy access to medical providers and medication adjustments significantly decreased asthma hospitalizations. It has not been demonstrated conclusively that an intensive ED-based asthma management program similar to these two models could prevent relapse following acute asthma treatment in the ED, but such programs seem worthy of further investigation.

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The therapeutic efficacy of live probiotic strains may be limited

Kuitunen reported that probiotic supplementation of pregnant mothers and their offspring conferred protection from allergic disease only to cesarean-delivered children, suggesting that probiotic treatment may be beneficial only in subpopulations of patients (ie, those with abnormal or disrupted gut microbiota). It is also clear that the immunoregulatory actions of certain LAB can be inhibited in the presence of other strains. L reuteri, a poor inducer of IL-12 from murine DCs, inhibits IL-12, IL-6, and TNF-a induction by the otherwise strong HQ Viagra online  cytokine inducer L casei, whereas both Bifidobacterium bifidum and L reuteri can inhibit Lactobacillus acidophilus-induced IL-12 production by DCs and accordingly abrogate IFN-g production by NK cells.

This suggests that the benefits of mixed strain probiotic preparations may actually be less than the sum of their parts. How the existing commensal LAB and other bacteria composing the host microbiota might influence immunomodulatory action of a single orally administered strain is also unknown. Other factors that have not been fully explored and may influence therapeutic efficacy include the fact that the immune response to candidate probiotics may depend on the growth phase of the bacteria. Furthermore, there has also been little examination of the immunomodulatory effects of long-term exposure to probiotics, and one study in mice suggests that some of the extraintestinal immune effects may be lost with sustained treatment.

Conclusions

For the reasons outlined previously, the therapeutic efficacy of live probiotic strains may be limited. However, alternative approaches may be developed. To date a number of microbial cell wall components, including polysaccharides! and lipoteichoic acids as well as potential secreted products, have been identified as being critical to the immunoregulatory effects of certain bacteria and/or to mimic the effect of whole organisms, including the ability to attenuate the allergic airway response in mice (Fig 2).

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Effects of BMI on Static Lung Volumes in Patients With Airway Obstruction

Such research may lead to the development of therapies that effectively deliver critical triggers to the innate immune system in such a way as to mimic the immu-noregulatory effects of whole probiotic organisms while bypassing some of the strain- and host-specific factors that might hinder the efficacy of live bacteria. Regardless of the approach taken, it is clear that without the identification of the critical characteristics of effective probiotic strains or a clear understanding of their mechanism of action, testing of probiotic-based treatment will remain highly empirical, and as such the outcome of clinical trials will continue to be variable and may serve to obfuscate the true potential of microbial-based therapies for respiratory disorders Viagra online Pharmacy.

Background: Both chronic airway obstruction and obesity are increasing in prevalence but the effect of their combination on pulmonary function parameters across the range of airway obstruction is unknown.

Methods: We studied the impact of increasing BMI on static lung volumes and airway function in a cohort of 2,265 subjects from a large pulmonary function laboratory database who were 40 to 80 years of age and met GOLD (Global Initiative for Chronic Obstructive Lung Disease) spirometric criteria for COPD (postbronchodilator FEV j/FVC < 0.7). We also evaluated the influence of severity of airway obstruction (by GOLD criteria) on these relationships.

Results: With increasing BMI in the group as a whole, functional residual capacity, residual volume, expiratory reserve volume, and specific airway resistance (sRaw) decreased exponentially (all P < .001); total lung capacity (TLC) decreased linearly (P < .001); and inspiratory capacity (IC) and IC/TLC increased linearly (P < .001). However, vital capacity was not influenced significantly. The effects of increasing BMI on FEV/FVC and sRaw were greatest in GOLD stage III/IV (P < .05), whereas increasing BMI had greater effects on IC in GOLD stage I (P < .001). Conclusions: With increasing BMI, subjects with airway obstruction had consistent reductions in lung hyperinflation, with significant improvements in IC and the FEV1/FVC ratio; this effect was greatest in patients with the most severe airway obstruction.

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The prevalence of obesity is increasing dramatically throughout the Western world

These results have important implications for the clinical assessment of patients with combined obesity and airway obstruction.

Abbreviations: AN OVA = analysis ofvariance; Dlco = diffusing capacity of the lung for carbon monoxide; ERV = expiratory reserve volume; FRC = functional residual capacity; GOLD = Global Initiative for Chronic Obstructive Lung Disease; IC = inspiratory capacity; LLN = lower limit of normal; NW = normal weight; OB = obese; OW = overweight; Raw = airway resistance; RV = residual volume; sRaw = specific airway resistance; TLC = total lung capacity; UW = underweight; VC = vital capacity.

The prevalence of obesity is increasing dramatically throughout the Western world. It is well established that obesity can result in respiratory impairment and increased respiratory symptoms, even in individuals without airway obstruction. The main physiologic effects of simple obesity include reduced respiratory system compliance, increased work and oxygen cost of breathing, and increased peripheral airway closure. In a cohort of individuals without airway obstruction (prebronchodilator FEV/FVC > 90% predicted), Jones and Nzekwui confirmed an inverse relation between increasing BMI and static lung volume components. In that study, it was established that relatively small increases in BMI (ie, the overweight [OW] range) had profound effects on functional © 2011 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians residual capacity (FRC) and expiratory reserve volume (ERV).

The interaction between increasing BMI and lung volumes in individuals with underlying airway obstruction is less well established. Recent studies in asthma have indicated that the relation between BMI and lung volumes appears to be similar to that described in populations without airway obstruction. Information Viagra Canada is lacking on the effect of BMI on plethysmo-graphic lung volume measurements in patients with COPD. This information becomes important for accurate interpretation of pulmonary function tests in an ever-increasing number of patients in whom obesity and chronic airway obstruction coexist.

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Heart and Respiratory Rates, Pulmonary Function, and Arterial Blood

Finally, only 6 patients (16.6%) in the 28% group presented a PaC02 increase > 2 mm Hg (mean increase, 3.4 ± 1.9 mm Hg; range, 2 to 5.9 mm Hg), compared with 16 patients (42.1%) [mean increase, 5.0 ± 3.8 mm Hg; range, 2.4 to 14.3 mm Hg] in the 100% group (p = 0.02). At the end of the protocol, this subgroup of patients showed a significant difference in PEFR (PEFR deterioration of 11.9 ± 30.0 L/min in the 100% group, compared with an increase of 18.3 ± 25.4 L/min in the 28% group, p = 0.03). Whereas PaC02 did not correlate with PEFR in the 28% group (r = 0.21, p = 0.6), the 100% group showed an inverse curvilinear correlation between PEFR before oxygen administration and PaC02 during oxygen treatment (Fig 2). Low values of PEFR were associated with high levels of PaC02 (r = 0.53, p = 0.01, polynomial model).

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Table 2—Heart and Respiratory Rates, Pulmonary Function, and Arterial Blood Gas Levels at 20 min of Oxygen

Variables 28% O2 (n = 36) 100% O2 (n = 38) p Value Mean Difference(95% CI)
Respiratory rate, breaths/min 20.6 ± 3.1 21.0 ± 3.6 0.6 – 0.4 (- 2.1 to 1.2)
Respiratory rate variation, breaths/min О1+

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– 1.2 ± 2.9 0.4 0.2 (- 0.9 to 1.5)
Heart rate, beats/min 92.2 ± 13.8 96.9 ± 17.0 0.2 – 4.7(11.8 to 2.5)
Heart rate variation, beats/min – 2.0 ± 6.4 – 4.9 ± 8.4 0.1 – 2.9 (- 0.6 to 6.3)
PEFR, L/min 219.7 ± 80.1 217.8 ± 61.9 0.8 2.6 (- 30.2 to 35.5)
PEFR, variation, L/min 24.1 ± 38.6 – 7.6 ± 23.7 0.001 31.7 (16.7 to 46.8)
pH 7.41 ± 0.04 7.38 ± 0.04 0.01 0.03 (0.00 to 0.05)
pH variation 0.00 ± 0.04 – 0.01 ± 0.04 0.04 0.01 (0.00 to 0.04)
PaC02, mm Hg 35.4 ± 4.4 38.0 ± 7.0 0.03 – 2.7 (- 4.7 to – 0.7)
PaC02 variation, mm Hg Go1+

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1.8 ± 3.9 0.001 – 3.1 (- 4.9 to – 1.3)
Pa0£, mm Hg 99.4 ± 16.3 257.8 ± 76.6 0.001 – 158.4 (- 185.1 to – 131.8)
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Treatment ED and antioxidants

As knowledge is power, you can now appreciate why we have spent some time explaining free radicals and the focus on antioxidants. So, what are these antioxidants?

Antioxidants neutralize free radicals by donating one of their own electrons, ending the electron “free for all” reaction. The antioxidants themselves don’t become free radicals by giving or taking an electron because they are stable in either form.

Our bodies naturally make certain anti-oxidant enzymes but we can also get them from the foods we eat. The best known anti-oxidants are beta carotene, vitamins C, A and E. Other anti-oxidants include ginkgo biloba, coenzyme Q10, tocotrienols, lycopene and polyphenols, which are substances found in most plants. There are also some minerals such as copper, zinc, manganese, selenium and other trace minerals which become antioxidants when they combine with body enzymes to fight baddie free radicals. There are many more.

Vitamins А, С, E and beta-carotene seem to work on their own or in conjunction with each other. Vitamin С is water soluble and can work in conjunction with vitamin E, which is fat soluble, and work on the cell membranes or inside the cells. Vitamin С can also clean free radical substances from vitamin E molecules so those molecules can continue to attack other free radicals. Beta-carotene converts to vitamin A, a powerful anti-oxidant, when there is a shortage of vitamin A in the body Viagra online Australia. Research has shown that antioxidants are much more effective when consumed in combinations and they are all important for different parts of the body. For instance, lycopene has been found to fight prostate issues.

So, your body needs as many antioxidants as possible and here some important points as evidenced by research. If you get an adequate supply of one anti-oxidant, it doesn’t mean you wouldn’t benefit by the use of another. There is also such a thing as too much of an anti-oxidant; Vitamin A can be toxic when taken in too large a quantity. A definitive study (PubMed 173275526) showed that Vitamin A and E may increase mortality! What I am getting at is that the best way to source these antioxidants is through your diet and you can stop wasting your money on supplements that beef up a particular antioxidant.

Let’s summarise what we have researched and learnt. Lifestyle and Nutrition choices are the inputs and stress and inflammation are the intermediaries that generate baddie free radicals. Stress and inflammation come from what you do, how you live and where you live your life: your Lifestyle. The best defence against baddie free radicals is reducing stress and inflammation and the body’s defence is from antioxidants which, are best sourced from Nutrition.

To give your Dick the best chance we should also aid the production of Nitric Oxide (NO) and boost your testosterone levels naturally without having to access supplementation through your Doctor. This is the basis of this Lifestyle & Nutrition Step and it is relevant for everyone.

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All about cancer (part 2)

Treatment Options for Cancer

Surgical removal of the tumour is usually the best treatment option if it is possible. Other options include chemotherapy or radiotherapy, which may be used on their own or in combination. The potential for the use of these treatments depends on many factors, including the type and location of the tumour, as well as whether and where else in the body the tumour has spread to. If radiotherapy or chemotherapy is used to treat a cancer along with surgery then this is called adjuvant chemotherapy or adjuvant radiotherapy.

Chemotherapy is medication that attacks cancer cells. Some forms can be given orally while others are given by injection into the blood vessels. There are different chemotherapy ‘cocktails’ used for different tumours. One of the main side effects of this treatment is a weakening of the immune system.

Radiotherapy is a treatment that uses beams of radiation to attack cancer cells. This is usually external to the body but recently, for prostate and breast cancers, radiation capsules are sometimes being placed inside the body to irradiate the tumour from the inside out.

Lung Cancer

Lung cancer usually starts in the lining of the tubes that bring air into the lungs. Lung cancers are believed to develop slowly over a period of many years.

What Are the Symptoms of Lung Cancer?

Lung cancer usually does not show symptoms when it first develops, but symptoms often appear when the tumour begins growing. Each individual may experience symptoms differently.

A persistent cough is the most common symptom of lung cancer. Other symptoms include:

  • Hoarseness
  • Blood-streaked sputum or phlegm (spit)
  • Constant chest pain
  • Feeling short of breath
  • Wheezing
  • Recurring lung infections, such as pneumonia or bronchitis
  • Unexplained fever
  • Low sodium levels, leading to confusion

Like all cancers, lung cancer can cause general symptoms such as loss of energy, fatigue, weight loss, loss of appetite, non-specific aches and pains, headaches and fractures. Direct pressure effects on large blood vessels or certain nerves near the lung can cause swelling of the neck and face or cause pain and weakness in the shoulder, arm or hand. Of course, some or all of these symptoms can be caused by many other conditions so make sure you consult your doctor for advice.

What Are the Main Risk Factors for Lung Cancer?

By far and away the most common cause of lung cancer is cigarette smoke. Heavy smokers are twenty-five times more likely to get lung cancer than non-smokers. The risk of lung cancer also applies to light smokers, who are ten times more likely to get lung cancer than non-smokers. Passive smoking, in other words breathing in someone else’s smoke, is also an increased risk factor for lung cancer.

Rarer causes of lung cancer include exposure to environmental carcinogens such as asbestos, arsenic or radon gas. The effects Viagra in Australia of exposure to these carcinogens can be much more lethal in smokers.

Smoking marijuana can result in even more tar getting to the lungs than cigarettes and is a recognised cause of lung cancer. As marijuana is an illegal substance, it is not possible to control whether it contains other harmful substances such as pesticides or other additives. Marijuana joints tend to be inhaled very deeply and smoked all the way to the end, where the tar content is the highest.

Chronic inflammation of the lungs such as from tuberculosis, some types of pneumonia and air pollution can also be potential risk factors for lung cancer.

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All About Cancer (Part 1)

Length of Exposure

Of course the likelihood of developing cancer from a carcinogen increases in relation to the intensity and length of exposure to that carcinogen. For example, someone who continues to eat a diet high in saturated animal fat and low in fresh fruit and vegetables is at higher risk of bowel and prostate cancer than a man who may have had a poor diet but has now made some positive changes. Smoking one cigarette once clearly has a negligible risk of lung cancer compared to smoking twenty cigarettes a day for thirty years.

Radon

Radon is the second leading cause of lung cancer after cigarette smoking. The World Health Organization has classified radon as a Class 1 carcinogen. When breathed into the lungs this radioactive gas damages lung tissues, which can lead to lung cancer. Radon is a naturally occurring gas that comes from the radioactive decay of uranium in our rocks and soils. It has no odour, colour or taste and so can not be detected by humans. There are parts of Ireland where radon gas levels are very high, including the south east. Radon dissolves and is harmless in the open air but in enclosed spaces like houses it can build up to dangerous levels. All new houses now have to be fitted with a radon barrier but any house built prior to 1998 does not have to have a radon barrier fitted. Therefore it is important to check radon levels in your own house. This can be done quite simply by getting a radon counter, which is available from the Radiological Protection Institute of Ireland in Dublin (RPII) (www.rpii.ie). The counter is left in your house for a period of time and then sent back to them for analysis. If the radon levels are high, then remedial measures can be taken to correct this. According to the RPII, radon accounts for about two-thirds of the total radiation to which the average Irish person is exposed. The lifetime risk of lung cancer for a 70-year-old man who has been exposed to high levels of radon is one in fifty.

General Warning Signs of Cancer – Catch it Early

While cancer is best prevented, early detection is vital to maximise the chance of cure. This means, as a man, you must be aware of potential early warning signs of cancer and take appropriate action. While many men with some of the listed symptoms won’t actually have cancer or other serious illnesses, it’s important not to take chances with your health. If in doubt, check it out! There really are no advantages to delaying seeking medical advice. On the contrary, early detection can literally sometimes be the difference between life and death.

  • Any change in your bowel habit such as bleeding from the back passage, constipation or diarrhoea, or a feeling of incomplete emptying may indicate early bowel cancer.
  • A change in your waterworks pattern, including urinating more often, the stream stopping and starting, peeing at night and with a sense of urgency, may indicate prostate problems.
  • A sore that doesn’t heal can suggest mouth or skin cancer.
  • Any obvious change in a mole or a wart, such as an increase in size, change in colour or bleeding, may indicate skin cancer.
  • Unusual bleeding from any site of the body:
    • blood in the stool may indicate colon cancer.
    • blood in the urine may indicate bladder cancer or kidney cancer.
    • spitting or coughing up blood may indicate lung cancer.
  • A lump or swelling in the testicles may indicate testicular cancer.
  • Persistent heartburn, indigestion, difficulty swallowing or feeling something getting stuck may indicate cancer of the food pipe (oesophagus) or stomach.
  • A persistent cough or chronic hoarseness may be a sign of throat or lung cancer.
  • Any nagging pain in the bones or elsewhere without apparent reason
  • Unexplained weight loss or loss of appetite
  • Persistent sweating
  • Low-grade fever
  • Unexplained bruising
  • Persistent headaches
  • Unusual fatigue
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An Exploration of Priorities for Adulthood and the Meaning of Parenthood

Meaning of parenthood

Previous research on ‘meaning of parenthood’ has fallen into two categories:

  1. undertaken with adults, largely in relation to infertility and new reproductive technologies
  2. undertaken with adolescents, largely in relation to prevention of teenage pregnancy.

Previous research with adults

For the majority of adults there is an expectation and desire to produce children. Research has suggested that ‘meaning of parenthood’ is a complex and individual concept with core components variously identified as biological, psychological, sociological, emotional, interpersonal and socio-cultural/ societal. A helpful review of the research in this area has been carried out by Netherwood.

Researchers have also sought to understand the continuing attraction of parenthood. Callan’s Australian research suggests this may be because virtually all societies are essentially pronatalistic, praising the virtues of parenthood and encouraging reproduction. In British culture, for example, research has shown that there is such a societal expectation to reproduce that those (in particular, women) who either voluntarily or involuntarily do not do so are seen as outside the norm. The stigma of childlessness, however, is by no means an exclusively female problem. Fathering a child is viewed socially as confirmation of a man’s virility and a childless man may feel that others doubt his masculinity.

Interestingly, the perceived disadvantages of parenthood receive much less coverage in published research. Morse notes her view that perceived disadvantages may include the inevitable return to traditional roles, with the woman caring for children and being responsible for domestic chores while the man is the primary or only breadwinner; the real or perceived reduction in income and associated financial difficulties; the curtailment of leisure activities; and the prevention of the full experience and expression of an adult relationship because of the presence of a child. An Australian Pharmacy Online study of voluntarily and involuntarily childless wives’ perceptions of motherhood included disruptions to lifestyle, lack of personal time and prevention of opportunities for adult development and learning.

A review of changing population trends over the past 25 years suggests the need to understand better voluntary childlessness. The number of child-less women of 40 years of age in Britain has risen from one in ten in 1980 to one in five in 2000 with women now expected to have an average of 1.7 children each – one of the lowest figures since wartime. As Bunting points out, this trend is not unique to Britain. Although it is commonly assumed that every adult expects and wants to produce children, the prevalence of involuntary childlessness in industrialized societies is around 15–19 per cent and research suggests that between 4 per cent and 9 per cent never seek or want parenthood, preferring instead to pursue careers, enjoy life free from parental responsibilities and commit to relationships without reproduction.

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