Heart and Respiratory Rates, Pulmonary Function, and Arterial Blood

Finally, only 6 patients (16.6%) in the 28% group presented a PaC02 increase > 2 mm Hg (mean increase, 3.4 ± 1.9 mm Hg; range, 2 to 5.9 mm Hg), compared with 16 patients (42.1%) [mean increase, 5.0 ± 3.8 mm Hg; range, 2.4 to 14.3 mm Hg] in the 100% group (p = 0.02). At the end of the protocol, this subgroup of patients showed a significant difference in PEFR (PEFR deterioration of 11.9 ± 30.0 L/min in the 100% group, compared with an increase of 18.3 ± 25.4 L/min in the 28% group, p = 0.03). Whereas PaC02 did not correlate with PEFR in the 28% group (r = 0.21, p = 0.6), the 100% group showed an inverse curvilinear correlation between PEFR before oxygen administration and PaC02 during oxygen treatment (Fig 2). Low values of PEFR were associated with high levels of PaC02 (r = 0.53, p = 0.01, polynomial model).

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Table 2—Heart and Respiratory Rates, Pulmonary Function, and Arterial Blood Gas Levels at 20 min of Oxygen

Variables 28% O2 (n = 36) 100% O2 (n = 38) p Value Mean Difference(95% CI)
Respiratory rate, breaths/min 20.6 ± 3.1 21.0 ± 3.6 0.6 – 0.4 (- 2.1 to 1.2)
Respiratory rate variation, breaths/min О1+

to

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– 1.2 ± 2.9 0.4 0.2 (- 0.9 to 1.5)
Heart rate, beats/min 92.2 ± 13.8 96.9 ± 17.0 0.2 – 4.7(11.8 to 2.5)
Heart rate variation, beats/min – 2.0 ± 6.4 – 4.9 ± 8.4 0.1 – 2.9 (- 0.6 to 6.3)
PEFR, L/min 219.7 ± 80.1 217.8 ± 61.9 0.8 2.6 (- 30.2 to 35.5)
PEFR, variation, L/min 24.1 ± 38.6 – 7.6 ± 23.7 0.001 31.7 (16.7 to 46.8)
pH 7.41 ± 0.04 7.38 ± 0.04 0.01 0.03 (0.00 to 0.05)
pH variation 0.00 ± 0.04 – 0.01 ± 0.04 0.04 0.01 (0.00 to 0.04)
PaC02, mm Hg 35.4 ± 4.4 38.0 ± 7.0 0.03 – 2.7 (- 4.7 to – 0.7)
PaC02 variation, mm Hg Go1+

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1.8 ± 3.9 0.001 – 3.1 (- 4.9 to – 1.3)
Pa0£, mm Hg 99.4 ± 16.3 257.8 ± 76.6 0.001 – 158.4 (- 185.1 to – 131.8)
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